An airstrike would definitely be in order, unless they can lure the enemy out one by one and pick 'em off.

Wish I still had my Dizzy. He took out dozens of rats in our old apartment, sometimes several in a day. One carcass barely fit in a ten inch box for disposal. Fortunately, usually I'd just find the tails. He was unbelievably neat and tidy about it. And poof, no rat problem!