I agree that the increased risk does not seem large to me. (But then, "large" is a subjective judgment, and me, I'm already heavily biased in favor of using the stuff.) I also agree that this study is not at all a full picture.

I don't know much about the Celebrex study. 3.4 times (or 2.5 times) WHAT risk? The FDA did consider taking that one off the market. Fortunately for several people I know, they haven't taken that step.